SCHEMBL3824324

SCHEMBL3824324

CCCCOCC(C(=O)OCC)c1ccccc1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.45
TSHR P16473 3/20 0.43
TDP1 Q9NUW8 2/20 0.42
PPARG P37231 2/20 0.41
PPARA Q07869 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.40
MAPT P10636 2/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPK1 P28482 1/20 0.40
LMNA P02545 3/20 0.40
CYP1A2 P05177 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
PLIN1 O60240 1/20 0.40
PLIN5 Q00G26 1/20 0.40
ABHD5 Q8WTS1 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28914754 0.81 TSHR (0.47) NPSR1TSHRTDP1SMN1; SMN2MAPT
SCHEMBL16672989 0.80 POLB (0.46) NPSR1TSHRTDP1SMN1; SMN2MAPT
SCHEMBL30669705 0.80 POLB (0.48) NPSR1TDP1SMN1; SMN2MAPTALDH1A1
SCHEMBL7979095 0.80 POLB (0.48) NPSR1TDP1SMN1; SMN2MAPTALDH1A1
SCHEMBL7783985 0.78 SMN1; SMN2 (0.46) TSHRTDP1SMN1; SMN2MAPTALDH1A1
SCHEMBL7293335 0.77 MEN1 (0.46) NPSR1TSHRTDP1SMN1; SMN2MAPT
SCHEMBL21656310 0.77 POLB (0.46) NPSR1TDP1SMN1; SMN2MAPTALDH1A1
SCHEMBL14874462 0.75 MMP8 (0.50) NPSR1PPARGPPARAMAPTALDH1A1
SCHEMBL27923688 0.75 LMNA (0.46) NPSR1TDP1SMN1; SMN2MAPTLMNA
SCHEMBL28588425 0.75 ALDH1A1 (0.45) NPSR1TDP1SMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11192965-B2 Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2021-12-07 US disclosed
US-20210040247-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2021-02-11 US disclosed
CN-108473612-B Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2021-02-05 CN disclosed
EP-3404046-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST FOR POLYMERIZATION OF OLEFINS, AND METHOD FOR PRODUCING OLEFIN POLYMERS TOHO TITANIUM CO LTD (JP) 2020-08-19 EP disclosed
EP-3404046-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST FOR POLYMERIZATION OF OLEFINS, AND METHOD FOR PRODUCING OLEFIN POLYMERS Toho Titanium Co., Ltd. (JP) 2018-11-21 EP disclosed
EP-1355955-B1 CATALYST FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2009-08-26 EP disclosed
US-6906154-B2 Catalyst for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-06-14 US disclosed
EP-1355955-A1 CATALYST FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.p.A. (IT) 2003-10-29 EP disclosed
US-20030027715-A1 Catalyst for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A (IT) 2003-02-06 US disclosed
WO-2002044219-A1 CATALYST FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-06-06 WO disclosed
EP-1141044-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER Basell Technology Company B.V. (NL) 2001-10-10 EP disclosed
WO-2001036496-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-05-25 WO disclosed
EP-0383346-B1 Catalyst, process for its preparation and process for polymerization of olefins using this catalyst SHOWA DENKO KK (JP) 1995-05-03 EP disclosed
US-5041403-A Magnesium, titanium, halogen, ester compound, and organic aluminum compound SHOWA DENKO K.K. (JP) 1991-08-20 US disclosed