SCHEMBL3824481

SCHEMBL3824481

O=C1c2ccc(C(c3ccc4c(c3)C(=O)N(OS(=O)(=O)c3ccc([N+](=O)[O-])cc3)C4=O)(C(F)(F)F)C(F)(F)F)cc2C(=O)N1OS(=O)(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.46
MEN1 O00255 1/20 0.46
VDR P11473 2/20 0.43
KDM4E B2RXH2 5/20 0.43
ALDH1A1 P00352 5/20 0.43
HPGD P15428 4/20 0.43
MAPT P10636 3/20 0.43
CA1 P00915 5/20 0.40
CA2 P00918 5/20 0.40
CA9 Q16790 5/20 0.40
CA12 O43570 5/20 0.40
F2 P00734 2/20 0.40
HSD11B1 P28845 1/20 0.40
CA5A P35218 1/20 0.39
CA4 P22748 2/20 0.39
MASP2 O00187 1/20 0.38
ALOX5 P09917 1/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3824343 0.87 KMT2A (0.51) KMT2AMEN1VDRKDM4EALDH1A1
SCHEMBL3824392 0.87 KMT2A (0.62) KMT2AMEN1VDRKDM4EALDH1A1
SCHEMBL3826650 0.86 VDR (0.60) KMT2AMEN1VDRKDM4EALDH1A1
SCHEMBL3823040 0.85 KDM4E (0.52) KMT2AMEN1VDRKDM4EALDH1A1
SCHEMBL3828348 0.85 KDM4E (0.52) KMT2AMEN1VDRKDM4EALDH1A1
SCHEMBL3824476 0.85 KMT2A (0.49) KMT2AMEN1VDRKDM4EALDH1A1
SCHEMBL3823299 0.84 KDM4E (0.62) KMT2AMEN1VDRKDM4EALDH1A1
SCHEMBL3828282 0.83 KMT2A (0.47) KMT2AMEN1VDRKDM4EALDH1A1
SCHEMBL3823256 0.83 KMT2A (0.47) KMT2AMEN1VDRKDM4EALDH1A1
SCHEMBL6420990 0.82 KMT2A (0.46) KMT2AMEN1VDRKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1449833-B1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION WAKO PURE CHEM IND LTD (JP) 2009-09-09 EP disclosed
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 KMT2A 1016/4885MEN1 211/4885VDR 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.