Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MELK | Q14680 | 3/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831162 | 0.84 | RAB9A (0.53) | RAB9AHTR1ADRD2DRD4HTR2A | |
| SCHEMBL3823684 | 0.84 | KDM4E (0.45) | RAB9ACHIAHTR1ADRD2DRD4 | |
| SCHEMBL3048291 | 0.84 | KCNH2 (0.45) | MCHR1KCNH2MELKPRKAA2CA12 | |
| SCHEMBL3825171 | 0.84 | RAB9A (0.53) | RAB9AHTR1ADRD2DRD4HTR2A | |
| Hydrochloric Acid SCHEMBL3822406 | 0.83 | RAB9A (0.52) | RAB9AHTR1ADRD2DRD4HTR2A | |
| SCHEMBL8170943 | 0.83 | L3MBTL1 (0.43) | RAB9ACHIAHTR1ADRD2DRD4 | |
| SCHEMBL3826499 | 0.82 | HTR1A (0.46) | RAB9AHTR1ADRD2DRD4HTR2A | |
| SCHEMBL3826843 | 0.82 | MAPKAPK2 (0.47) | RAB9AHTR1ADRD2DRD4HTR2A | |
| SCHEMBL3823664 | 0.82 | MAPT (0.53) | RAB9AHTR1ADRD2DRD4HTR2A | |
| SCHEMBL3830908 | 0.82 | HTR1A (0.45) | RAB9AHTR1ADRD2DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |