Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 1.00 |
| ▸ | HTR2B | P41595 | 17/20 | 1.00 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818396 | 1.00 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL5132606 | 1.00 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL8857937 | 0.80 | HTR2C (0.71) | HTR2CHTR2BHTR2A | |
| SCHEMBL11824870 | 0.79 | HTR2C (0.77) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL2017216 | 0.79 | HTR2C (0.65) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL11884695 | 0.76 | HTR2C (0.73) | HTR2CHTR2BHTR2A | |
| SCHEMBL697549 | 0.76 | HTR2C (0.61) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL2018076 | 0.76 | HTR2C (0.61) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL3265754 | 0.76 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL30396809 | 0.76 | HTR2C (1.00) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953161-B1 | New tricyclic derivatives, method of preparing same and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008110691-A1 | NOVEL TRICYCLIC DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2008-09-18 | — | — | WO | disclosed |
| EP-1953161-A1 | New tricyclic derivatives, method of preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2008-08-06 | — | — | EP | disclosed |