SCHEMBL3824569

SCHEMBL3824569

CCOP(=O)(O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
PPARD Q03181 2/20 0.41
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GRM4 Q14833 1/20 0.33
HMGCR P04035 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
SMPD1 P17405 1/20 0.31
LPAR1 Q92633 2/20 0.31
LPAR3 Q9UBY5 2/20 0.31
LPAR2 Q9HBW0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8413442 0.87 PPARD (0.36) TSHRPPARDTP53TDP1
SCHEMBL12740886 0.82 PPARD (0.39) TSHRPPARDTP53TDP1GRM4
SCHEMBL3820534 0.82 LPAR3 (0.38) HMGCRSMPD1LPAR1LPAR3LPAR2
SCHEMBL13557185 0.81 PPARD (0.32) PPARD
SCHEMBL28881876 0.81 TSHR (0.42) TSHRPPARDTP53TDP1SMPD1
SCHEMBL19940080 0.81 BTN3A1 (0.35) TSHRLPAR1LPAR3LPAR2
Diethyl Hydrogen Phosphate SCHEMBL31413319 0.79 TP53 (0.52) TSHRPPARDTP53TDP1CA12
SCHEMBL990567 0.79
SCHEMBL22588854 0.79 TSHR (0.40) TSHRPPARDTP53TDP1HMGCR
SCHEMBL19940081 0.79 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12296304-B2 Membrane for water filtration AQUAPORIN A/S (DK) 2025-05-13 US disclosed
EP-4277731-B1 PROCESS FOR PREPARING A MEMBRANE AQUAPORIN AS (DK) 2024-10-09 EP disclosed
US-20240058768-A1 MEMBRANE FOR WATER FILTRATION AQUAPORIN A/S (DK) 2024-02-22 US disclosed
EP-4277731-A1 MEMBRANE FOR WATER FILTRATION Aquaporin A/S (DK) 2023-11-22 EP disclosed
CN-116745025-A membrane for water filtration 水通道蛋白有限公司 2023-09-12 CN disclosed
WO-2022152748-A1 MEMBRANE FOR WATER FILTRATION AQUAPORIN A/S (DK) 2022-07-21 WO disclosed
WO-2018140648-A1 PYRROLOPYRIMIDINE ITK INHIBITORS FOR TREATING INFLAMMATION AND CANCER JACOBSEN ERIC JON (US) 2018-08-02 WO disclosed
US-8106209-B2 Substituted aminothiazole prodrugs of compounds with anti-HCV activity ACHILLION PHARMACEUTICALS, INC. (US) 2012-01-31 US disclosed
US-20110086813-A1 COMPOUNDS FOR TREATING BACTERIAL INFECTIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2011-04-14 US disclosed
US-7745625-B2 Prodrugs of piperazine and substituted piperidine antiviral agents BRISTOL-MYERS SQUIBB COMPANY (US) 2010-06-29 US disclosed
US-6723241-B2 COMPRISING A POLYAMIDE LAYER ON A POROUS SUPPORT WHERE THE POLYAMIDE LAYER IS COMPLEXED OR HYDROGEN BONDED TO A PHOSPHORUS-CONTAINING COMPOUND; IMPROVED FLUX AND/OR REJECTION RATE; FILTERS; NANOFILTRATION AND REVERSE OSMOSIS DOW GLOBAL TECHNOLOGIES INC. 2004-04-20 US disclosed
CN-1441693-A Composite film and method for producing same DOW GLOBAL TECHNOLOGY CO (US) 2003-09-10 CN disclosed
US-20030116498-A1 Composite membrane and method for making the same THE DOW CHEMICAL COMPANY 2003-06-26 US disclosed
US-6562266-B2 Composite membrane and method for making the same DOW GLOBAL TECHNOLOGIES INC. 2003-05-13 US disclosed
EP-1276551-A2 COMPOSITE MEMBRANE AND METHOD FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2003-01-22 EP disclosed
US-20020113008-A1 Composite membrane and method for making the same THE DOW CHEMICAL COMPANY 2002-08-22 US disclosed
US-6337018-B1 COATING POROUS SUPPORT WITH SOLUTION OF POLYFUNCTIONAL AMINE AND SOLUTION OF POLYFUNCTIONAL ACYL HALIDE WHICH REACT TO FORM POLYAMIDE LAYER, INCLUDING STEP OF CONTACTING PHOSPHOROUS COMPOUND WITH ACYL HALIDE BEFORE REACTING WITH AMINE THE DOW CHEMICAL COMPANY 2002-01-08 US disclosed
US-20010050252-A1 Composite membrane and method for making the same DOW GLOBAL TECHNOLOGIES LLC 2001-12-13 US disclosed
WO-2001078882-A2 COMPOSITE MEMBRANE AND METHOD FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2001-10-25 WO disclosed
US-3954755-A INSECTICIDES, ACARICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110086813-A1 COMPOUNDS FOR TREATING BACTERIAL INFECTIONS REL, RELA, NFKB1 TSHR 4414/4885PPARD 4104/4885TP53 3100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.