Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555311 | 0.87 | KMT2A (0.44) | SMN1; SMN2HIF1AHSD11B1ALDH1A1RAB9A | |
| SCHEMBL8559898 | 0.83 | SLC1A3 (0.40) | SMN1; SMN2HIF1AHSD11B1ALDH1A1CYP2C19 | |
| SCHEMBL7374391 | 0.80 | HTT (0.42) | SMN1; SMN2HIF1AHSD11B1ALDH1A1 | |
| SCHEMBL382142 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1AHSD11B1TSHR | |
| SCHEMBL7651608 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1AHSD11B1TSHR | |
| Hydrochloric Acid SCHEMBL382912 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2HIF1AHSD11B1TSHR | |
| SCHEMBL2332617 | 0.74 | NSD2 (0.42) | SMN1; SMN2HIF1ACYP1A2 | |
| SCHEMBL2327649 | 0.73 | CA2 (0.55) | HIF1ATDP1CYP2C19CYP1A2 | |
| SCHEMBL27678465 | 0.71 | SLC1A3 (0.40) | SMN1; SMN2HIF1AHSD11B1RECQLTDP1 | |
| SCHEMBL7372959 | 0.70 | ALDH1A1 (0.45) | MMP1MMP13MMP9ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |