Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382490 | 0.87 | RBP4 (0.40) | ALDH1A1RAB9AHSD11B1GAATDP1 | |
| SCHEMBL8559898 | 0.79 | SLC1A3 (0.40) | KMT2AALDH1A1HSD11B1SMN1; SMN2HIF1A | |
| SCHEMBL7374391 | 0.79 | HTT (0.42) | KMT2AMEN1ALDH1A1HSD11B1SMN1; SMN2 | |
| SCHEMBL7651608 | 0.76 | SMN1; SMN2 (0.44) | KMT2AHSD11B1SMN1; SMN2HIF1AHTR6 | |
| SCHEMBL382142 | 0.76 | SMN1; SMN2 (0.44) | KMT2AHSD11B1SMN1; SMN2HIF1AHTR6 | |
| Hydrochloric Acid SCHEMBL382912 | 0.74 | SMN1; SMN2 (0.43) | KMT2AHSD11B1SMN1; SMN2HIF1AHTR6 | |
| Trifluoroacetic Acid SCHEMBL15918323 | 0.73 | KMT2A (0.49) | KMT2AMEN1ALDH1A1RAB9AKAT6A | |
| SCHEMBL8619624 | 0.73 | KIF11 (0.44) | KMT2AMEN1ALDH1A1MMP7HSD11B1 | |
| SCHEMBL2332617 | 0.72 | NSD2 (0.42) | SMN1; SMN2HIF1A | |
| SCHEMBL8557198 | 0.71 | CA1 (0.49) | KMT2AMEN1RAB9AMMP7KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1996038426-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-05 | — | — | WO | claimed |