Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 4/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.35 |
| ▸ | APEX1 | P27695 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 4/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.35 |
| ▸ | BLM | P54132 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826523 | 0.96 | LMNA (0.47) | LMNATDP1SLC7A11THRBF11 | |
| Potassium Ion SCHEMBL3820804 | 0.96 | LMNA (0.42) | LMNATDP1SLC7A11THRBF11 | |
| Lithium Ion SCHEMBL20497214 | 0.87 | SLC7A11 (0.55) | LMNATDP1SLC7A11MAPTPKM | |
| Lithium Ion SCHEMBL3826188 | 0.79 | DUSP5 (0.47) | LMNATDP1THRBF11POLB | |
| SCHEMBL8892659 | 0.76 | DUSP5 (0.49) | LMNATDP1SLC7A11THRBF11 | |
| SCHEMBL6380334 | 0.76 | DUSP5 (0.49) | LMNATDP1SLC7A11THRBF11 | |
| SCHEMBL30708661 | 0.76 | DUSP5 (0.49) | LMNATDP1SLC7A11THRBF11 | |
| Potassium Ion SCHEMBL6385050 | 0.76 | DUSP5 (0.45) | LMNATDP1SLC7A11THRBF11 | |
| Naphthalene Trisulfonate SCHEMBL3821831 | 0.75 | SIRT1 (0.44) | LMNATDP1THRBPOLBCYP3A4 | |
| Lithium Ion SCHEMBL3818493 | 0.75 | NR1I2 (0.45) | LMNATDP1THRBHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2105477-A1 | Method of forming inkjet image | FUJIFILM Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |
| US-20090238973-A1 | Method of forming inkjet image | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |