Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.45 |
| ▸ | DUSP5 | Q16690 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892659 | 1.00 | DUSP5 (0.49) | DUSP5PTPN1THRBTSHRRECQL | |
| SCHEMBL30708661 | 1.00 | DUSP5 (0.49) | DUSP5PTPN1THRBTSHRRECQL | |
| Potassium Ion SCHEMBL6385050 | 0.96 | DUSP5 (0.45) | DUSP5PTPN1THRBTSHRRECQL | |
| SCHEMBL3816117 | 0.86 | DUSP5 (0.52) | DUSP5PTPN1THRBTSHRRECQL | |
| SCHEMBL30683817 | 0.84 | DUSP5 (0.55) | DUSP5PTPN1THRBTSHRRECQL | |
| SCHEMBL29385780 | 0.84 | THRB (0.47) | DUSP5THRBTSHRRECQLHSD17B10 | |
| SCHEMBL6690494 | 0.84 | THRB (0.47) | DUSP5THRBTSHRRECQLHSD17B10 | |
| SCHEMBL127422 | 0.84 | THRB (0.47) | DUSP5THRBTSHRRECQLHSD17B10 | |
| Potassium Ion SCHEMBL3817947 | 0.82 | DUSP5 (0.47) | DUSP5PTPN1TSHRRECQLHSD17B10 | |
| Lithium Ion SCHEMBL3826188 | 0.82 | DUSP5 (0.47) | DUSP5PTPN1THRBTSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222455-A1 | Method for producing 3-hydroxy-2-methylbenzoic acid | BAYER CHEMICALS AG (DE) | 2005-10-06 | — | — | US | claimed |
| US-6891060-B2 | Preparation of 3-acyloxy-2-methylbenzoic acids | BAYERAKTIENGESELLSCHAFT (DE) | 2005-05-10 | — | — | US | claimed |
| EP-1490319-A2 | METHOD FOR PRODUCING 3-HYDROXY-2-METHYLBENZOIC ACID | Bayer Chemicals AG (DE) | 2004-12-29 | — | — | EP | claimed |
| US-20040044243-A1 | Preparation of 3-acyloxy-2-methylbenzoic acids | LANXESS DEUTSCHLAND GMBH (DE) | 2004-03-04 | — | — | US | claimed |
| WO-2003080542-A2 | METHOD FOR PRODUCING 3-HYDROXY-2-METHYLBENZOIC ACID | BAYER CHEMICALS AG (DE) | 2003-10-02 | — | — | WO | claimed |
| CN-117468059-A | Silver graphene electroplating solution and electric contact conductor | 温州泰钰新材料科技有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-20180048011-A1 | HIGH pH ORGANIC FLOW BATTERY | U.S. DEPARTMENT OF ENERGY | 2018-02-15 | — | — | US | disclosed |
| WO-2016144909-A9 | HIGH pH ORGANIC FLOW BATTERY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-06-15 | — | — | WO | disclosed |
| WO-2016144909-A1 | HIGH pH ORGANIC FLOW BATTERY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-15 | — | — | WO | disclosed |
| US-20050222455-A1 | Method for producing 3-hydroxy-2-methylbenzoic acid | BAYER CHEMICALS AG (DE) | 2005-10-06 | — | — | US | disclosed |
| US-6891060-B2 | Preparation of 3-acyloxy-2-methylbenzoic acids | BAYERAKTIENGESELLSCHAFT (DE) | 2005-05-10 | — | — | US | disclosed |
| EP-1490319-A2 | METHOD FOR PRODUCING 3-HYDROXY-2-METHYLBENZOIC ACID | Bayer Chemicals AG (DE) | 2004-12-29 | — | — | EP | disclosed |
| EP-1237853-A1 | A PROCESS FOR REMOVING TRACE SOLVENT FROM A MATERIAL | Warner Lambert Research and Development Ireland Limited (IE) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044173-A1 | A PROCESS FOR REMOVING TRACE SOLVENT FROM A MATERIAL | WARNER LAMBERT RESEARCH AND DEVELOPMENT IRELAND LIMITED (IE) | 2001-06-21 | — | — | WO | disclosed |
| WO-1999027939-A1 | UREIDO DERIVATIVES OF POLY-4-AMINO-2-CARBOXY-1-METHYL PYRROLE COMPOUNDS FOR INHIBITION OF INFLAMMATION | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-06-10 | — | — | WO | disclosed |
| US-5593976-A | New ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds | FARMITALIA CARLO ERBA S R L (IT) | 1997-01-14 | — | — | US | disclosed |
| EP-0462258-B1 | UREIDO DERIVATIVES OF POLY-4-AMINO-2-CARBOXY-1-METHYL COMPOUNDS | PHARMACIA SPA (IT) | 1995-12-20 | — | — | EP | disclosed |
| US-5420296-A | Ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds | FARMITALIA CARLO ERBA S R L (IT) | 1995-05-30 | — | — | US | disclosed |
| US-5260329-A | Ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds | FARMITALIA CARLO ERBA SRL (IT) | 1993-11-09 | — | — | US | disclosed |
| WO-1991010649-A1 | NEW UREIDO DERIVATIVES OF POLY-4-AMINO-2-CARBOXY-1-METHYL COMPOUNDS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1991-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044243-A1 | Preparation of 3-acyloxy-2-methylbenzoic acids | TET2, NAAA, APEH | THRB 4256/4885DUSP5 4448/4885PTPN1 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.