Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 13/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821458 | 1.00 | ADK (0.57) | ADKADORA3LMNATSHRMAPT | |
| SCHEMBL23098378 | 0.85 | ADK (0.56) | ADKADORA3LMNATSHRMAPT | |
| SCHEMBL10013535 | 0.84 | LMNA (0.56) | ADKADORA3LMNATSHRMAPT | |
| SCHEMBL3827614 | 0.84 | ADK (0.57) | ADKADORA3LMNATSHRMAPT | |
| SCHEMBL12029778 | 0.84 | LMNA (0.56) | ADKADORA3LMNATSHRMAPT | |
| SCHEMBL19657131 | 0.84 | LMNA (0.56) | ADKADORA3LMNATSHRMAPT | |
| SCHEMBL15119375 | 0.84 | LMNA (0.56) | ADKADORA3LMNATSHRMAPT | |
| SCHEMBL2467656 | 0.84 | LMNA (0.56) | ADKADORA3LMNATSHRMAPT | |
| SCHEMBL331945 | 0.84 | LMNA (0.56) | ADKADORA3LMNATSHRMAPT | |
| SCHEMBL13621266 | 0.84 | LMNA (0.56) | ADKADORA3LMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882734-B1 | 5'-Deoxy-cytidine derivatives | HOFFMANN LA ROCHE (CH) | 2009-08-26 | — | — | EP | claimed |
| EP-0882734-A2 | 5'-Deoxy-cytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-12-09 | — | — | EP | claimed |
| EP-0882734-B1 | 5'-Deoxy-cytidine derivatives | HOFFMANN LA ROCHE (CH) | 2009-08-26 | — | — | EP | disclosed |
| US-6211166-B1 | COADMINISTERED WITH A 5-FLUOROURACIL DERIVATIVE; ANTICARCINOGENIC AGENTS | HOFFMAN-LA ROCHE INC. | 2001-04-03 | — | — | US | disclosed |
| US-6114520-A | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0882734-A2 | 5'-Deoxy-cytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-12-09 | — | — | EP | disclosed |