Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | ADK | P55263 | 10/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302008 | 1.00 | LMNA (0.56) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL331944 | 1.00 | LMNA (0.56) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL13621266 | 1.00 | LMNA (0.56) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL12029778 | 1.00 | LMNA (0.56) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL10041945 | 1.00 | LMNA (0.56) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL15119375 | 1.00 | LMNA (0.56) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL331945 | 1.00 | LMNA (0.56) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL19657131 | 1.00 | LMNA (0.56) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL10013535 | 1.00 | LMNA (0.56) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL13126803 | 1.00 | LMNA (0.56) | LMNATSHRMAPTPMP22HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | TECHFIELDS PHARMA CO., LTD (CN) | 2023-07-27 | — | — | US | disclosed |
| US-11541029-B2 | High penetration compositions and their applications | TECHFIELDS PHARMA CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| EP-2370406-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | Yu, Chongxi (US) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010065936-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | YU CHONGXI (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20090209754-A1 | Process for the preparation of capecitabine | PLUS CHEMICALS S.A. (CH) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209754-A1 | Process for the preparation of capecitabine | TYMP, DPYD, TYMS | LMNA 2780/4885TSHR 4054/4885MAPT 4058/4885 |
| US-11541029-B2 | High penetration compositions and their applications | SLC19A1, HIRA, SLC43A1 | LMNA 1775/4885TSHR 4827/4885MAPT 1754/4885 |
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | SLC5A7, SLC19A1, SLC43A1 | LMNA 2635/4885TSHR 4760/4885MAPT 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.