Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.53 |
| ▸ | ITGAV | P06756 | 11/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382797 | 0.95 | ITGB3 (0.46) | ITGB3ITGA2BITGAVMMP13NR1H2 | |
| SCHEMBL7860282 | 0.92 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL7860298 | 0.92 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL382574 | 0.88 | ITGAV (0.47) | ITGB3ITGA2BITGAV | |
| SCHEMBL382554 | 0.87 | MMP13 (0.39) | ITGB3ITGA2BITGAVMMP13NR1H2 | |
| SCHEMBL383113 | 0.87 | ITGB3 (0.45) | ITGB3ITGA2BITGAV | |
| SCHEMBL383380 | 0.86 | ITGB3 (0.45) | ITGB3ITGA2BITGAV | |
| SCHEMBL382798 | 0.86 | NR1H2 (0.38) | ITGB3ITGA2BITGAVMMP13NR1H2 | |
| SCHEMBL382606 | 0.84 | SMN1; SMN2 (0.42) | ITGB3ITGA2BITGAVNR1H2 | |
| SCHEMBL383504 | 0.83 | ITGAV (0.42) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | claimed |
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |