Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382554 | 0.95 | MMP13 (0.39) | NR1H2NR1H3ALKITGB3ITGAV | |
| SCHEMBL383114 | 0.92 | MAPT (0.39) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL7860398 | 0.88 | SMN1; SMN2 (0.36) | NR1H2ITGB3ITGAVITGA2BLMNA | |
| SCHEMBL7860292 | 0.87 | MAPT (0.39) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL382797 | 0.86 | ITGB3 (0.46) | NR1H2NR1H3ALKITGB3ITGAV | |
| SCHEMBL382553 | 0.86 | ITGB3 (0.53) | NR1H2NR1H3ITGB3ITGAVITGA2B | |
| SCHEMBL382575 | 0.83 | SMN1; SMN2 (0.36) | NR1H2ITGB3ITGAVITGA2BLMNA | |
| SCHEMBL382605 | 0.79 | CASR (0.41) | NR1H2ALKLMNAKCNH2KDM4E | |
| SCHEMBL383113 | 0.78 | ITGB3 (0.45) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL7860298 | 0.78 | ITGB3 (0.51) | ITGB3ITGAVITGA2BALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |