Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5808141 | 0.83 | CA1 (0.51) | STAT3CA1CA2CA9CA12 | |
| SCHEMBL3826487 | 0.82 | CA2 (0.41) | STAT3CA1CA2CA9CA12 | |
| SCHEMBL3823915 | 0.80 | STAT3 (0.47) | STAT3CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL5808221 | 0.78 | STAT3 (0.49) | STAT3CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL5805298 | 0.77 | STAT3 (0.45) | STAT3CA1CA2CA9CA12 | |
| SCHEMBL2069124 | 0.77 | CA2 (0.52) | CA1CA2CA9CA12CA4 | |
| SCHEMBL3819210 | 0.76 | STAT3 (0.47) | STAT3CA1CA2CA9CA12 | |
| SCHEMBL22606378 | 0.76 | STAT3 (0.69) | STAT3CA1CA2CA9CA12 | |
| SCHEMBL27957398 | 0.75 | STAT3 (0.63) | STAT3CA1CA2CA9CA12 | |
| SCHEMBL7194865 | 0.75 | CA2 (0.50) | CA1CA2CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129365-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2009-10-22 | — | — | WO | disclosed |