Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.41 |
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA6 | P23280 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826484 | 0.82 | STAT3 (0.45) | CA2CA1CA9CA12CA6 | |
| SCHEMBL4435159 | 0.81 | CA2 (0.51) | CA2CA1CA9CA12CA6 | |
| SCHEMBL3823918 | 0.79 | LRRK2 (0.44) | CA2CA1CA9CA12CA6 | |
| Hydrochloric Acid SCHEMBL5808145 | 0.79 | CA2 (0.50) | CA2CA1CA9CA12CA6 | |
| SCHEMBL2069124 | 0.78 | CA2 (0.52) | CA2CA1CA9CA12CA6 | |
| Hydrochloric Acid SCHEMBL5808223 | 0.77 | CA2 (0.43) | CA2CA1CA9CA12CA6 | |
| SCHEMBL2896796 | 0.77 | LRRK2 (0.51) | CA2CA1CA9CA12CA6 | |
| Hydrochloric Acid SCHEMBL5805303 | 0.77 | PTGES2 (0.44) | CA2CA1CA9CA12CA6 | |
| SCHEMBL7194865 | 0.76 | CA2 (0.50) | CA2CA1CA9CA12CA6 | |
| SCHEMBL3819215 | 0.75 | CA2 (0.44) | CA2CA1CA9CA12CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129365-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2009-10-22 | — | — | WO | disclosed |