SCHEMBL2069124

SCHEMBL2069124

CC(C)(C)c1ccccc1S(N)(=O)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.52
CA1 P00915 11/20 0.52
CA9 Q16790 9/20 0.52
CA5A P35218 5/20 0.52
CA6 P23280 4/20 0.52
CA12 O43570 4/20 0.52
CA4 P22748 3/20 0.52
CA7 P43166 3/20 0.52
CA5B Q9Y2D0 3/20 0.52
CA14 Q9ULX7 2/20 0.52
CYP2C9 P11712 1/20 0.52
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
RBP4 P02753 1/20 0.44
HSD11B1 P28845 1/20 0.44
CA3 P07451 1/20 0.41
PLA2G7 Q13093 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
LDHA P00338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7194865 0.98 CA2 (0.50) CA2CA1CA9CA5ACA6
SCHEMBL28345243 0.86 CA2 (0.52) CA2CA1CA9CA5ACA6
SCHEMBL17093012 0.86 CA2 (0.52) CA2CA1CA9CA5ACA6
SCHEMBL19857593 0.83 HSD11B1 (0.49) CA2CA1CA9CA5ACA6
SCHEMBL9360088 0.81 HSD11B1 (0.54) CA2ALDH1A1TSHRTDP1RBP4
SCHEMBL302570 0.80 MEN1 (0.56) CA2CA1CA9CA5ACA6
SCHEMBL29418255 0.80 MEN1 (0.56) CA2CA1CA9CA5ACA6
SCHEMBL7283144 0.79 CA2 (0.41) CA2CA1CA9CA5ACA6
SCHEMBL10407302 0.79 CA2 (0.45) CA2CA1CA9CA5ACA6
SCHEMBL10587163 0.79 CA2 (0.45) CA2CA1CA9CA5ACA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3218357-A1 3,4-DIAMINOBENZENESULFONAMIDE DERIVATIVES FOR INHIBITING CELL DEATH VIB vzw (BE) 2017-09-20 EP claimed
CN-103626742-B Bi-aryl meta-pyrimidine inhibitors of kinases 塔格根公司 2017-04-26 CN claimed
WO-2016075330-A1 3,4-DIAMINOBENZENESULFONAMIDE DERIVATIVES FOR INHIBITING CELL DEATH VIB VZW (BE) 2016-05-19 WO claimed
CN-105392816-A Heat resistant polyethylene terephthalate and a process for the preparation of the same ESTER IND LTD 2016-03-09 CN claimed
CN-102250020-A Method for preparing N-[6-chloro-5-(2-methoxyphenoxy)[2,2'-dipyridine]-4-yl]-4-tertiary butyl-benzsulfamide JINAN DACHENG PHARMACEUTICAL DEV CO LTD 2011-11-23 CN claimed
EP-4735420-A1 ARYL INDOL-3-YL KETONE AND ARYL INDAZOL-3-YL KETONE INHIBITORS OF KIF18A Volastra Therapeutics, Inc. (US) 2026-05-06 EP disclosed
WO-2025007055-A1 ARYL INDOL-3-YL KETONE AND ARYL INDAZOL-3-YL KETONE INHIBITORS OF KIF18A VOLASTRA THERAPEUTICS, INC. (US) 2025-01-02 WO disclosed
CN-117865987-A Antitumor compounds 法马马有限公司 2024-04-12 CN disclosed
US-11787799-B2 Potent antiviral pyrazolopyridine compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-17 US disclosed
US-11787799-B2 Potent antiviral pyrazolopyridine compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-17 US disclosed
US-11701370-B2 Phosphonium ion channel blockers and methods for use Nocion Therapeutics, Inc. (US) 2023-07-18 US disclosed
US-11701370-B2 Phosphonium ion channel blockers and methods for use Nocion Therapeutics, Inc. (US) 2023-07-18 US disclosed
US-4655821-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-07 US disclosed
EP-0212779-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-03-04 EP disclosed
US-4589909-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-05-20 US disclosed
US-4543120-A HERBICIDES, PLATN GROWTH REGULANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-09-24 US disclosed
US-4514211-A HERBICIDES, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-30 US disclosed
EP-0101308-A2 Alkyl sulfonyl sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-22 EP disclosed
US-4371391-A TRIAZIN-2-YL-AMINO CARBONYL BENZENE SURLONAMIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-02-01 US disclosed
EP-0048143-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11787799-B2 Potent antiviral pyrazolopyridine compounds MAVS, VRK1, VRK2 CA2 1980/4885CA1 4053/4885CA9 2806/4885
US-11701370-B2 Phosphonium ion channel blockers and methods for use TRPV1, TRPV5, TRPA1 CA2 154/4885CA1 674/4885CA9 1428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.