Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400175 | 0.76 | CA1 (0.42) | KMT2ALMNATDP1MAPTALDH1A1 | |
| SCHEMBL722599 | 0.72 | BCAT1 (0.46) | BCAT1KMT2ALMNATDP1MAPT | |
| SCHEMBL31215190 | 0.72 | BCAT1 (0.46) | BCAT1KMT2ALMNATDP1MAPT | |
| Water SCHEMBL27820714 | 0.71 | BCAT1 (0.44) | BCAT1KMT2ALMNATDP1MAPT | |
| SCHEMBL6261806 | 0.71 | BCAT1 (0.44) | BCAT1KMT2ALMNATDP1MAPT | |
| SCHEMBL106041 | 0.70 | BCAT1 (0.42) | BCAT1KMT2AKDM4ELMNATDP1 | |
| SCHEMBL9456389 | 0.70 | NR1I2 (0.38) | KMT2APOLBLMNATDP1ALDH1A1 | |
| SCHEMBL3830874 | 0.69 | BCAT1 (0.47) | BCAT1KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL3830877 | 0.69 | BCAT1 (0.47) | BCAT1KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL835147 | 0.69 | ALDH1A1 (0.44) | POLBKDM4ELMNATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099757-A2 | SULFOXIMINES AS KINASE INHIBITORS | Allergan, Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008061236-A2 | SULFOXIMINES AS KINASE INHIBITORS | ALLERGAN, INC. (US) | 2008-05-22 | — | — | WO | disclosed |