SCHEMBL3826641

SCHEMBL3826641

CCCCCCCCCCCCNC(=N)NC(=N)Nc1ccc(Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
EPHX1 P07099 7/20 0.47
ALDH1A1 P00352 1/20 0.44
HTT P42858 1/20 0.44
EPHX2 P34913 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorhexidine SCHEMBL21680261 1.00 LMNA (0.55) LMNASMN1; SMN2EPHX1ALDH1A1HTT
SCHEMBL12522772 1.00 LMNA (0.55) LMNASMN1; SMN2EPHX1ALDH1A1HTT
SCHEMBL13400831 0.99 SMN1; SMN2 (0.56) LMNASMN1; SMN2EPHX1ALDH1A1HTT
SCHEMBL10015687 0.94 SMN1; SMN2 (0.61) LMNASMN1; SMN2HTT
Chlorhexidine SCHEMBL1898352 0.93 LMNA (0.49) LMNASMN1; SMN2EPHX1ALDH1A1HTT
Chlorhexidine SCHEMBL14603395 0.93 LMNA (0.48) LMNASMN1; SMN2ALDH1A1HTT
Chlorhexidine SCHEMBL1550787 0.93 LMNA (0.46) LMNASMN1; SMN2ALDH1A1HTT
Chlorhexidine SCHEMBL3984 0.93 LMNA (0.46) LMNASMN1; SMN2ALDH1A1HTT
Chlorhexidine SCHEMBL1551122 0.93 LMNA (0.46) LMNASMN1; SMN2ALDH1A1HTT
SCHEMBL6365499 0.93 LMNA (0.46) LMNASMN1; SMN2ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450294-B2 Shampoo compositions LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-05-28 US disclosed
WO-2012119155-A1 ANTIMICROBIAL COMPOSITIONS FOR TOOTH FLUORIDATION AND REMINERALIZATION AMERICAN DENTAL ASSOCIATION FOUNDATION (US) 2012-09-07 WO disclosed
EP-1841402-B9 PROCESS FOR PREPARING HYDROCOLLOIDS LUBRIZOL ADVANCED MAT INC (US) 2009-09-16 EP disclosed
US-20090137438-A1 Hydrocolloids and Process Therefor LUBRIZOL ADVANCED MATERIALS, INC. 2009-05-28 US disclosed
EP-1841402-B1 PROCESS FOR PREPARING HYDROCOLLOIDS LUBRIZOL ADVANCED MAT INC (US) 2009-04-22 EP disclosed
EP-1841402-A1 PROCESS FOR PREPARING HYDROCOLLOIDS Lubrizol Advanced Materials, Inc. (US) 2007-10-10 EP disclosed
US-20070187429-A1 Dual opening tubular dispenser FARAHMAND BARDIA 2007-08-16 US disclosed
WO-2006065469-A1 PROCESS FOR PREPARING HYDROCOLLOIDS NOVEON, INC. (US) 2006-06-22 WO disclosed
WO-2006062792-A2 HYDROCOLLOIDS AND PROCESS THEREFOR NOVEON, INC. (US) 2006-06-15 WO disclosed
EP-1639018-A1 GALACTOMANNAN HYDROCOLLOIDS Noveon IP Holdings Corp. (US) 2006-03-29 EP disclosed
US-20050075497-A1 Hydrocolloids and process therefor LUBRIZOL ADVANCED MATERIALS, INC. 2005-04-07 US disclosed
WO-2004113390-A1 GALACTOMANNAN HYDROCOLLOIDS NOVEON IP HOLDINGS CORP. (US) 2004-12-29 WO disclosed
US-6200550-B1 Oral care compositions comprising coenzyme Q10 Q-PHARMA, INC. 2001-03-13 US disclosed
EP-0575020-A1 Non-aqueous liquid antibacterial oral composition exhibiting improved uptake on dental tissue surfaces Colgate-Palmolive Company (US) 1993-12-22 EP disclosed
EP-0372603-A2 Antibacterial oral composition Colgate-Palmolive Company (US) 1990-06-13 EP disclosed
EP-0040738-A2 Dentifrices Richardson-Vicks, Inc. (US) 1981-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137438-A1 Hydrocolloids and Process Therefor ALG1, GYPA, HSD17B7 LMNA 2846/4885SMN1; SMN2 4513/4885EPHX1 1460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.