Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Chlorhexidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorhexidine SCHEMBL14603395 | 0.94 | LMNA (0.48) | LMNASMN1; SMN2CNR1SLC6A3MEN1 | |
| Chlorhexidine SCHEMBL3984 | 0.94 | LMNA (0.46) | LMNASMN1; SMN2CNR1SLC6A3MEN1 | |
| Chlorhexidine SCHEMBL1551122 | 0.94 | LMNA (0.46) | LMNASMN1; SMN2CNR1SLC6A3MEN1 | |
| SCHEMBL6365499 | 0.94 | LMNA (0.46) | LMNASMN1; SMN2CNR1SLC6A3MEN1 | |
| Chlorhexidine SCHEMBL1550787 | 0.94 | LMNA (0.46) | LMNASMN1; SMN2CNR1SLC6A3MEN1 | |
| SCHEMBL3826641 | 0.93 | LMNA (0.55) | LMNASMN1; SMN2EPHX1ALDH1A1HTT | |
| Chlorhexidine SCHEMBL21680261 | 0.93 | LMNA (0.55) | LMNASMN1; SMN2EPHX1ALDH1A1HTT | |
| SCHEMBL12522772 | 0.93 | LMNA (0.55) | LMNASMN1; SMN2EPHX1ALDH1A1HTT | |
| Chlorhexidine SCHEMBL23533285 | 0.93 | LMNA (0.43) | LMNASMN1; SMN2CNR1SLC6A3MEN1 | |
| Chlorhexidine SCHEMBL6433032 | 0.92 | LMNA (0.45) | LMNASMN1; SMN2CNR1SLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-214340262-U | Anti-fogging mask | 中国人民解放军陆军特色医学中心 | 2021-10-08 | — | — | CN | claimed |
| CN-214259831-U | Nursing bag for transfusion port | 河南省人民医院 | 2021-09-24 | — | — | CN | claimed |
| CN-111202088-A | Chlorhexidine acetate disinfectant and preparation method and application thereof | 吉林云飞医药有限公司 | 2020-05-29 | — | — | CN | claimed |
| US-5753246-A | Packaged germicidal towelette, sanitation kit and method for promoting hygiene | PETERS MARLIN W (US) | 1998-05-19 | — | — | US | claimed |
| CN-112368778-B | Method and use for providing educational guidance for peripheral IV therapy | 贝克顿·迪金森公司 | 2024-07-16 | — | — | CN | disclosed |
| WO-2023131355-A1 | WATER-SOLUBLE CHLORHEXIDINE ANTIBACTERIAL, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 江南大学 | 2023-07-13 | — | — | WO | disclosed |
| CN-115881288-B | Vein catheterization management system | 四川省肿瘤医院 | 2023-05-12 | — | — | CN | disclosed |
| CN-115881288-A | Vein catheterization management system | 四川省肿瘤医院 | 2023-03-31 | — | — | CN | disclosed |
| CN-114391550-B | Water-soluble chlorhexidine antibacterial agent and preparation method and application thereof | 江南大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-114391550-A | Water-soluble chlorhexidine antibacterial agent and preparation method and application thereof | 江南大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-214475487-U | Infusion connects disinfection reminding device | 武汉大学 | 2021-10-22 | — | — | CN | disclosed |
| CN-214259831-U | Nursing bag for transfusion port | 河南省人民医院 | 2021-09-24 | — | — | CN | disclosed |
| US-20020061286-A1 | Wipe with improved cleansing | BANK OF AMERICA, N.A., AS COLLATERAL AGENT | 2002-05-23 | — | — | US | disclosed |
| WO-2002000817-A1 | WIPE WITH IMPROVED CLEANSING | PLAYTEX PRODUCTS, INC. (US) | 2002-01-03 | — | — | WO | disclosed |
| US-6086578-A | Method for skin rejuvenation | ZAKRYTOYE AKTSIONERNOYE OBSCHESTO "OSTMEDKONSALT" (RU) | 2000-07-11 | — | — | US | disclosed |
| US-5753246-A | Packaged germicidal towelette, sanitation kit and method for promoting hygiene | PETERS MARLIN W (US) | 1998-05-19 | — | — | US | disclosed |
| US-5753246-A | Packaged germicidal towelette, sanitation kit and method for promoting hygiene | PETERS MARLIN W (US) | 1998-05-19 | — | — | US | disclosed |
| US-4981678-A | ALCOHOLIC CHLORHEXIDINE | SOLTEC RESEARCH PTY., LTD. (AU) | 1991-01-01 | — | — | US | disclosed |
| US-4915934-A | CORROSION INHIBITOR | CONNETICS AUSTRALIA PTY. LTD. (AU) | 1990-04-10 | — | — | US | disclosed |
| US-4301803-A | Balloon catheter | KURARAY CO., LTD. (JP) | 1981-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061286-A1 | Wipe with improved cleansing | CENPE, CHAT, PHOSPHO1 | LMNA 3296/4885SMN1; SMN2 895/4885CNR1 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.