SCHEMBL3826858

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28936624	0.83	HRH2 (0.50)	MAOBMAPTHRH2HRH1
	SCHEMBL11728742	0.75	MAOB (0.54)	MAOBTSHRNPC1RAB9APKM
	SCHEMBL7814459	0.75	MAOB (0.54)	MAOBNPC1RAB9APKMNFKB1
	SCHEMBL6323844	0.74	RAB9A (0.42)	MAOBTSHRNPC1RAB9APKM
	SCHEMBL6326645	0.72	L3MBTL1 (0.40)	NPC1RAB9APKMNFKB1NFKB2
	SCHEMBL6913209	0.72	TDP1 (0.71)	NPC1RAB9ASMN1; SMN2MAPTLMNA
	SCHEMBL6156819	0.72	TDP1 (0.71)	NPC1RAB9ASMN1; SMN2MAPTLMNA
	SCHEMBL4172632	0.72	TDP1 (0.71)	NPC1RAB9ASMN1; SMN2MAPTLMNA
	SCHEMBL29048469	0.72	TDP1 (0.71)	NPC1RAB9ASMN1; SMN2MAPTLMNA
	SCHEMBL5795584	0.72	MAOB (0.48)	MAOBNPC1RAB9APKMNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.