SCHEMBL3827005

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8183699	0.88	STIM1 (0.47)	EEDSTIM1ORAI1IDO1TDO2
	Hydrochloric Acid SCHEMBL3824937	0.87	STIM1 (0.46)	EEDSTIM1ORAI1IDO1TDO2
	SCHEMBL987860	0.82	TRPV1 (0.45)	MEN1MAPTKMT2ASTIM1ORAI1
	Hydrochloric Acid SCHEMBL3559784	0.81	TRPV1 (0.44)	MEN1MAPTKMT2ASTIM1ORAI1
	SCHEMBL615209	0.81	ALDH1A1 (0.41)	MEN1ALDH1A1KDM4EMAPTMAPK1
	SCHEMBL1783736	0.80	TRPV1 (0.44)	MEN1ALDH1A1MAPTKMT2AIDO1
	SCHEMBL1781223	0.80	RAB9A (0.47)	MEN1ALDH1A1KDM4EMAPTKMT2A
	SCHEMBL10819913	0.80	TRPV1 (0.43)	MEN1KMT2ASTIM1ORAI1TRPV1
	SCHEMBL3824697	0.79	TRPV1 (0.42)	MEN1MAPTKMT2ASTIM1ORAI1
	SCHEMBL3827342	0.77	TRPV1 (0.43)	ALDH1A1MAPTMAPK1KMT2ATRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.