Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826565 | 0.81 | SMN1; SMN2 (0.47) | NPC1RAB9AMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6509011 | 0.74 | F10 (0.52) | NPC1RAB9AMAOBF10SMN1; SMN2 | |
| SCHEMBL6527832 | 0.74 | NPC1 (0.52) | NPC1RAB9AF10SMN1; SMN2ALDH1A1 | |
| SCHEMBL3831190 | 0.72 | SMN1; SMN2 (0.55) | NPC1RAB9AMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6517565 | 0.72 | NPC1 (0.44) | NPC1RAB9AMAOBF10SMN1; SMN2 | |
| SCHEMBL5945165 | 0.72 | MGAT2 (0.43) | NPC1RAB9AMAOBF10SMN1; SMN2 | |
| SCHEMBL6512014 | 0.71 | F13A1 (0.47) | NPC1RAB9AF10SMN1; SMN2MAPT | |
| SCHEMBL6527452 | 0.71 | NPC1 (0.51) | NPC1RAB9AMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6529831 | 0.69 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL7008912 | 0.68 | NPC1 (0.59) | NPC1RAB9AMAOBSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318431-A1 | BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER INC. | 2009-12-24 | — | — | US | disclosed |
| EP-1987025-B1 | BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PROD INC (US) | 2009-09-16 | — | — | EP | disclosed |
| EP-1987025-A1 | BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pfizer Products Incorporated (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093904-A1 | BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318431-A1 | BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | HRH2, HRH1, HRH4 | NPC1 3535/4885RAB9A 4433/4885MAOB 931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.