Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1951995 | 0.89 | MET (0.53) | METCDKL5 | |
| SCHEMBL3825985 | 0.85 | MET (0.52) | METCDKL5 | |
| SCHEMBL3825945 | 0.82 | MET (0.54) | METCDKL5 | |
| SCHEMBL1952042 | 0.81 | MET (0.55) | METCDKL5 | |
| SCHEMBL837508 | 0.81 | MET (0.54) | METCDKL5 | |
| SCHEMBL12096358 | 0.79 | MET (0.46) | METCDKL5 | |
| SCHEMBL1951254 | 0.79 | MET (0.81) | METCDKL5 | |
| SCHEMBL1951680 | 0.79 | MET (0.67) | METCDKL5 | |
| SCHEMBL1953122 | 0.77 | MET (0.54) | METCDKL5 | |
| SCHEMBL1951173 | 0.76 | MET (0.43) | METCDKL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099447-A1 | IMIDAZOTRIAZINES AND IMIDAZOPYRIMIDINES AS KINASE INHIBITORS | Incyte Corporation (US) | 2009-09-16 | — | — | EP | claimed |
| WO-2008064157-A1 | IMIDAZOTRIAZINES AND IMIDAZOPYRIMIDINES AS KINASE INHIBITORS | INCYTE CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |