Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 7/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26956144 | 0.87 | HTR2C (0.43) | PDE4APDE4BPDE4CPDE4DHTR2C | |
| SCHEMBL7673770 | 0.78 | ROCK2 (0.54) | HTR2C | |
| SCHEMBL3858800 | 0.77 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DHTR2C | |
| SCHEMBL8198999 | 0.76 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4DHTR2C | |
| SCHEMBL3850521 | 0.76 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4DHTR2C | |
| SCHEMBL7963965 | 0.75 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24440866 | 0.74 | HTR2C (0.34) | PDE4APDE4BPDE4CPDE4DHTR2C | |
| SCHEMBL25669137 | 0.74 | CHRNA7 (0.39) | — | |
| SCHEMBL2045579 | 0.74 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18464323 | 0.73 | NR3C1 (0.47) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140417-A1 | METHODS FOR DELAY OF EJACULATION IN HUMAN MALES | KANNA HEALTH LTD. (GB) | 2022-06-30 | — | — | WO | disclosed |
| EP-2102168-A1 | ACYLAMINOPYRAZOLES FOR TREATING CARDIOVASCULAR DISEASES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008046527-A1 | ACYLAMINOPYRAZOLES FOR TREATING CARDIOVASCULAR DISEASES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-04-24 | — | — | WO | disclosed |