Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 12/20 | 0.51 |
| ▸ | RARB | P10826 | 12/20 | 0.51 |
| ▸ | RARG | P13631 | 12/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382090 | 0.90 | RARA (0.48) | RARARARBRARGHSD17B10NPC1 | |
| SCHEMBL381882 | 0.86 | RARG (0.66) | RARARARBRARG | |
| SCHEMBL382380 | 0.80 | RARB (0.42) | RARARARBRARGHSD17B10NPC1 | |
| SCHEMBL383525 | 0.80 | RARG (0.62) | RARARARBRARGHSD17B10NPC1 | |
| SCHEMBL4576213 | 0.79 | RARA (0.49) | RARARARBRARGHSD17B10KDM4E | |
| SCHEMBL380874 | 0.77 | RARA (0.51) | RARARARBRARGHSD17B10NPC1 | |
| SCHEMBL382839 | 0.77 | RARG (0.44) | RARARARBRARGKDM4ESMN1; SMN2 | |
| SCHEMBL382766 | 0.76 | RARG (0.65) | RARARARBRARG | |
| SCHEMBL4577375 | 0.76 | RARB (0.51) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL3439183 | 0.75 | RARG (0.63) | RARARARBRARGDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | disclosed |