Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824666 | 0.87 | GSK3B (0.66) | MAPTRAB9ASMN1; SMN2HTTGSK3B | |
| SCHEMBL9094196 | 0.87 | SLC2A1 (0.67) | SLC2A1MAPTRAB9ASMN1; SMN2HTT | |
| SCHEMBL14982059 | 0.86 | RAB9A (0.54) | MAPTRAB9ASMN1; SMN2HTTTP53 | |
| SCHEMBL10471535 | 0.84 | SLC2A1 (0.55) | SLC2A1MAPTRAB9ASMN1; SMN2HTT | |
| SCHEMBL9827103 | 0.84 | PRKDC (0.55) | SLC2A1MAPTRAB9ASMN1; SMN2HTT | |
| SCHEMBL14982133 | 0.80 | GSK3B (0.58) | MAPTRAB9ASMN1; SMN2GSK3BTP53 | |
| SCHEMBL14982132 | 0.80 | ALDH1A1 (0.61) | MAPTRAB9ASMN1; SMN2GSK3BTP53 | |
| SCHEMBL1663460 | 0.80 | MAPT (0.69) | MAPTRAB9ASMN1; SMN2HTTTP53 | |
| SCHEMBL18492951 | 0.79 | PRKDC (0.56) | SLC2A1MAPTRAB9ASMN1; SMN2HTT | |
| SCHEMBL10472739 | 0.79 | SLC2A1 (0.49) | SLC2A1MAPTRAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999835-B1 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | TAIJI BIOMEDICAL INC (US) | 2009-09-09 | — | — | EP | disclosed |
| US-5840721-A | INCREASE SENSITIVITY OF MULTIDRUG RESISTANT TUMOR CELLS TO ANTICANCER AGENTS | ONTOGEN CORPORATION (US) | 1998-11-24 | — | — | US | disclosed |