SCHEMBL3828837

SCHEMBL3828837

Cn1c(C(F)(F)F)cc(=O)n(-c2cc(OC(C(=O)O)C(=O)O)c(Cl)cc2F)c1=O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPOX P50336 4/20 0.36
DHODH Q02127 11/20 0.35
BCAT2 O15382 3/20 0.32
BCAT1 P54687 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7719036 0.91 PPOX (0.40) PPOXDHODH
SCHEMBL4572159 0.91 PPOX (0.40) PPOXDHODH
SCHEMBL2149762 0.91 PPOX (0.40) PPOXDHODH
SCHEMBL21307583 0.90 PPOX (0.36) PPOXDHODHBCAT2BCAT1
SCHEMBL31442494 0.89 PPOX (0.34) PPOXDHODHBCAT2BCAT1
SCHEMBL14571353 0.88 PPOX (0.34) PPOXDHODHBCAT2BCAT1
SCHEMBL30467089 0.88 PPOX (0.34) PPOXDHODHBCAT2BCAT1
SCHEMBL6638125 0.87 PPOX (0.34) PPOXDHODHBCAT2BCAT1
SCHEMBL10577861 0.87 PPOX (0.36) PPOXDHODHBCAT2BCAT1
SCHEMBL9541517 0.87 PPOX (0.44) PPOXDHODHBCAT2BCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1422227-B1 PROCESS FOR PRODUCING PYRIDINE COMPOUND SUMITOMO CHEMICAL CO (JP) 2009-09-09 EP disclosed
US-7223862-B2 Pyridone compounds useful for producing pyridine compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-29 US disclosed
US-20060189484-A1 PYRIDONE COMPOUNDS USEFUL FOR PRODUCING PYRIDINE COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-24 US disclosed
EP-1422227-A1 PROCESS FOR PRODUCING PYRIDINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060189484-A1 PYRIDONE COMPOUNDS USEFUL FOR PRODUCING PYRIDINE COMPOUNDS CBR3, CBR1, PNPO PPOX 213/4885DHODH 77/4885BCAT2 1679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.