Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 7/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 3/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576117 | 0.91 | PPOX (0.45) | PPOXMEN1NR1I2KMT2ATDP1 | |
| SCHEMBL10577861 | 0.91 | PPOX (0.36) | PPOXDHODHBCAT2BCAT1 | |
| SCHEMBL10577492 | 0.89 | PPOX (0.37) | PPOXDHODH | |
| SCHEMBL2149762 | 0.88 | PPOX (0.40) | PPOXDHODH | |
| SCHEMBL7782676 | 0.88 | PPOX (0.40) | PPOXDHODH | |
| SCHEMBL9050670 | 0.88 | PPOX (0.35) | PPOXDHODHBCAT2BCAT1 | |
| SCHEMBL7719036 | 0.88 | PPOX (0.40) | PPOXDHODH | |
| SCHEMBL4572159 | 0.88 | PPOX (0.40) | PPOXDHODH | |
| SCHEMBL10579188 | 0.88 | PPOX (0.34) | PPOXDHODHBCAT2BCAT1 | |
| SCHEMBL7019344 | 0.88 | PPOX (0.43) | PPOXMEN1NR1I2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255047-A1 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | claimed |
| US-7586023-B1 | Methods of conferring ppo-inhibiting herbicide resistance to plants by gene manipulation | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-09-08 | — | — | US | disclosed |
| WO-1993011669-A1 | USE OF 3-PHENYLURACIL DERIVATIVES FOR THE DESICCATION AND ABSCISSION OF PLANT PARTS | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-24 | — | — | WO | disclosed |
| US-4859229-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0255047-A1 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |