Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15529186 | 0.88 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL2921634 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL2921638 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL3072548 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL30253292 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL3829294 | 0.80 | MAPT (0.44) | ALDH1A1MAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL3829304 | 0.80 | MAPT (0.44) | ALDH1A1MAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL1812248 | 0.77 | S1PR4 (0.52) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL1810729 | 0.75 | S1PR4 (0.51) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL30365901 | 0.75 | NPC1 (0.49) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796466-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-1846416-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-07-01 | — | — | EP | disclosed |
| EP-2007377-A2 | ANTIBACTERIAL AGENTS | Glaxo Group Limited (GB) | 2008-12-31 | — | — | EP | disclosed |
| EP-1846416-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-10-24 | — | — | EP | disclosed |
| WO-2007118130-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-10-18 | — | — | WO | disclosed |
| EP-1796466-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006081178-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-08-03 | — | — | WO | disclosed |
| WO-2006002047-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-01-05 | — | — | WO | disclosed |