Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829294 | 1.00 | MAPT (0.44) | MAPTL3MBTL1ALDH1A1RAB9ANPC1 | |
| SCHEMBL2921634 | 0.93 | ALDH1A1 (0.47) | MAPTL3MBTL1ALDH1A1RAB9ANPC1 | |
| SCHEMBL2921638 | 0.93 | ALDH1A1 (0.47) | MAPTL3MBTL1ALDH1A1RAB9ANPC1 | |
| SCHEMBL15529186 | 0.82 | ALDH1A1 (0.47) | MAPTL3MBTL1ALDH1A1RAB9ANPC1 | |
| SCHEMBL3829296 | 0.80 | ALDH1A1 (0.45) | MAPTL3MBTL1ALDH1A1RAB9ANPC1 | |
| SCHEMBL1809848 | 0.80 | SMN1; SMN2 (0.37) | MAPTL3MBTL1ALDH1A1RAB9ANPC1 | |
| SCHEMBL30152695 | 0.80 | SMN1; SMN2 (0.37) | MAPTL3MBTL1ALDH1A1RAB9ANPC1 | |
| SCHEMBL30253292 | 0.77 | ALDH1A1 (0.48) | MAPTL3MBTL1ALDH1A1RAB9ANPC1 | |
| SCHEMBL3072548 | 0.77 | ALDH1A1 (0.48) | MAPTL3MBTL1ALDH1A1RAB9ANPC1 | |
| SCHEMBL1812248 | 0.74 | S1PR4 (0.52) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796466-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-1846416-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-07-01 | — | — | EP | disclosed |
| EP-2007377-A2 | ANTIBACTERIAL AGENTS | Glaxo Group Limited (GB) | 2008-12-31 | — | — | EP | disclosed |
| EP-1846416-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-10-24 | — | — | EP | disclosed |
| WO-2007118130-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-10-18 | — | — | WO | disclosed |
| EP-1796466-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006081178-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-08-03 | — | — | WO | disclosed |
| WO-2006002047-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-01-05 | — | — | WO | disclosed |