Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL3844851 | 0.90 | POLB (0.45) | DGKAFAAHPOLBMEN1KMT2A | |
| SCHEMBL3825321 | 0.86 | MEN1 (0.47) | DGKAFAAHPOLBMEN1KMT2A | |
| SCHEMBL3825328 | 0.86 | MEN1 (0.47) | DGKAFAAHPOLBMEN1KMT2A | |
| SCHEMBL688297 | 0.85 | POLB (0.49) | FAAHPOLBMEN1KMT2ACYP2C19 | |
| SCHEMBL1360713 | 0.85 | POLB (0.49) | FAAHPOLBMEN1KMT2ACYP2C19 | |
| SCHEMBL3844849 | 0.83 | MEN1 (0.40) | FAAHMEN1KMT2ACYP2C19L3MBTL1 | |
| SCHEMBL2889307 | 0.83 | POLB (0.49) | FAAHPOLBMEN1KMT2ACYP2C19 | |
| SCHEMBL3823823 | 0.82 | MEN1 (0.40) | FAAHMEN1KMT2ACYP2C19L3MBTL1 | |
| SCHEMBL3823832 | 0.82 | MEN1 (0.40) | FAAHMEN1KMT2ACYP2C19L3MBTL1 | |
| Monoethanolamine SCHEMBL2889305 | 0.81 | L3MBTL1 (0.43) | FAAHPOLBMEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | disclosed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |