Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 17/20 | 0.56 |
| ▸ | RARG | P13631 | 17/20 | 0.56 |
| ▸ | RARA | P10276 | 15/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382330 | 0.90 | RARA (0.46) | RARBRARGRARA | |
| SCHEMBL382170 | 0.85 | RARG (0.70) | RARBRARGRARAHSP90AA1HSP90AB1 | |
| SCHEMBL381528 | 0.85 | RARG (0.79) | RARBRARGRARA | |
| SCHEMBL382215 | 0.84 | RARG (0.77) | RARBRARGRARA | |
| SCHEMBL382732 | 0.83 | RARG (0.65) | RARBRARGRARAGAA | |
| SCHEMBL383242 | 0.83 | RARG (0.79) | RARBRARGRARA | |
| SCHEMBL382683 | 0.82 | RARG (0.78) | RARBRARGRARAGAA | |
| SCHEMBL382183 | 0.82 | RARG (0.80) | RARBRARGRARA | |
| SCHEMBL382210 | 0.82 | RARB (0.57) | RARBRARGRARAHSP90AA1HSP90AB1 | |
| SCHEMBL382238 | 0.81 | RARG (0.65) | RARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | claimed |