Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ILK | Q13418 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293356 | 0.79 | ALDH1A1 (0.66) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL3071959 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL335937 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL5497048 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL21753703 | 0.76 | ALDH1A1 (1.00) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL7268236 | 0.72 | ALDH1A1 (0.56) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL19783180 | 0.67 | ALDH1A1 (0.42) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL23463047 | 0.62 | ALDH1A1 (0.44) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL25424505 | 0.60 | ALDH1A1 (0.71) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL12844692 | 0.60 | GFER (0.61) | ALDH1A1LMNARAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089354-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008054154-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |