Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ILK | Q13418 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293356 | 0.79 | ALDH1A1 (0.66) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL3071959 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL5497048 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL21753703 | 0.76 | ALDH1A1 (1.00) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL1748249 | 0.76 | RAB9A (0.56) | ALDH1A1LMNARAB9ANPC1KMT2A | |
| SCHEMBL23290946 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNARAB9ANPC1KMT2A | |
| SCHEMBL1748298 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNARAB9ANPC1KMT2A | |
| SCHEMBL3829665 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAILKRAB9ANPC1 | |
| SCHEMBL12210694 | 0.73 | NSD1 (0.39) | ALDH1A1LMNARAB9ANPC1KMT2A | |
| SCHEMBL8331402 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNARAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296914-B | Derivatives with PPAR agonist activity | SHIONOGI & CO | 2012-07-18 | — | — | CN | disclosed |
| US-8097610-B2 | Derivative having PPAR agonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090286974-A1 | Derivative having ppar agonistic activity | SHIONOGI & CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
| CN-101296914-A | Derivatives with PPAR agonist activity | SHIONOGI & CO (JP) | 2008-10-29 | — | — | CN | disclosed |
| EP-1939189-A1 | DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286974-A1 | Derivative having ppar agonistic activity | PPARD, PPARA, PPARG | ALDH1A1 1821/4885LMNA 2761/4885ILK 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.