Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.44 |
| ▸ | ITGAV | P06756 | 9/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382789 | 0.91 | ITGB3 (0.45) | ITGB3ITGAVITGA2BCXCR3LMNA | |
| SCHEMBL7660996 | 0.87 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL382970 | 0.86 | ITGB3 (0.39) | ITGB3ITGAVITGA2BHTR2ACCR5 | |
| SCHEMBL7659630 | 0.84 | ITGB3 (0.48) | ITGB3ITGAVITGA2BLMNAMAPT | |
| SCHEMBL7656305 | 0.82 | ITGB3 (0.51) | ITGB3ITGAVITGA2BLMNAMAPT | |
| SCHEMBL7660986 | 0.82 | ITGB3 (0.40) | ITGB3ITGAVITGA2BCXCR3CCR5 | |
| SCHEMBL382401 | 0.79 | ITGB3 (0.46) | ITGB3ITGAVITGA2BLMNAMAPT | |
| SCHEMBL383255 | 0.79 | MAPT (0.40) | ITGB3ITGAVITGA2BHTR2AMAPT | |
| SCHEMBL7659624 | 0.78 | ITGB3 (0.41) | ITGB3ITGAVITGA2BCCR5LMNA | |
| SCHEMBL382788 | 0.76 | ITGB3 (0.39) | ITGB3ITGAVITGA2BCCR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |