Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.39 |
| ▸ | ITGAV | P06756 | 4/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660986 | 0.88 | ITGB3 (0.40) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382971 | 0.86 | ITGB3 (0.44) | ITGB3ITGAVITGA2BHTR2ACCR5 | |
| SCHEMBL7659624 | 0.85 | ITGB3 (0.41) | ITGB3ITGAVITGA2BCCR5F10 | |
| SCHEMBL382788 | 0.83 | ITGB3 (0.39) | ITGB3ITGAVITGA2BCCR5F10 | |
| SCHEMBL7656296 | 0.83 | ITGB3 (0.39) | ITGB3ITGAVITGA2BCCR5F10 | |
| SCHEMBL7660996 | 0.82 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL382399 | 0.79 | ITGB3 (0.40) | ITGB3ITGAVITGA2BKMT2ACHRM4 | |
| SCHEMBL382789 | 0.78 | ITGB3 (0.45) | ITGB3ITGAVITGA2BKMT2AF10 | |
| SCHEMBL7659630 | 0.78 | ITGB3 (0.48) | ITGB3ITGAVITGA2BKMT2AF10 | |
| SCHEMBL383255 | 0.78 | MAPT (0.40) | ITGB3ITGAVITGA2BHTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |