Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.48 |
| ▸ | ITGAV | P06756 | 7/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.48 |
| ▸ | TPH1 | P17752 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | GIPR | P48546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656305 | 0.90 | ITGB3 (0.51) | ITGB3ITGAVITGA2BF10MAPT | |
| SCHEMBL382789 | 0.88 | ITGB3 (0.45) | ITGB3ITGAVITGA2BF10MAPT | |
| SCHEMBL7659624 | 0.86 | ITGB3 (0.41) | ITGB3ITGAVITGA2BF10MAPT | |
| SCHEMBL383255 | 0.86 | MAPT (0.40) | ITGB3ITGAVITGA2BF10MAPT | |
| SCHEMBL7660996 | 0.86 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL7656296 | 0.84 | ITGB3 (0.39) | ITGB3ITGAVITGA2BF10MAPT | |
| SCHEMBL382971 | 0.84 | ITGB3 (0.44) | ITGB3ITGAVITGA2BF10MAPT | |
| SCHEMBL382788 | 0.82 | ITGB3 (0.39) | ITGB3ITGAVITGA2BF10MAPT | |
| SCHEMBL7660986 | 0.81 | ITGB3 (0.40) | ITGB3ITGAVITGA2BF10LMNA | |
| SCHEMBL382882 | 0.80 | ITGB3 (0.52) | ITGB3ITGAVITGA2BMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | claimed |
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |