Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830139 | 1.00 | ALDH1A1 (0.32) | ALDH1A1HPGDSMN1; SMN2P2RX4BCHE | |
| SCHEMBL6034344 | 0.98 | ALDH1A1 (0.33) | ALDH1A1HPGDSMN1; SMN2P2RX4BCHE | |
| SCHEMBL3588715 | 0.77 | MAPK1 (0.35) | SMN1; SMN2TSHR | |
| SCHEMBL27930086 | 0.76 | RAB9A (0.38) | ALDH1A1HPGDSMN1; SMN2P2RX4TSHR | |
| SCHEMBL4540593 | 0.74 | — | — | |
| SCHEMBL4771331 | 0.74 | TSHR (0.35) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL3797610 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL4774116 | 0.73 | TSHR (0.34) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL1838102 | 0.73 | PREP (0.37) | ALDH1A1HPGDSMN1; SMN2BCHE | |
| SCHEMBL5771784 | 0.72 | TSHR (0.39) | ALDH1A1HPGDSMN1; SMN2P2RX4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098512-A1 | Compounds and methods for treating dyslipidemia | Eli Lilly & Company (US) | 2009-09-09 | — | — | EP | claimed |