Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5967869 | 0.87 | RAB9A (0.43) | RAB9AHDAC2JAK2JAK1MEN1 | |
| SCHEMBL5568829 | 0.83 | RAB9A (0.43) | RAB9AHDAC2P2RX4CHRNB2CHRNA4 | |
| SCHEMBL1692767 | 0.80 | RAB9A (0.45) | RAB9AHDAC2P2RX4CHRNB2CHRNA4 | |
| SCHEMBL2229068 | 0.78 | RAB9A (0.44) | RAB9AHDAC2P2RX4CHRNB2CHRNA4 | |
| SCHEMBL14243062 | 0.76 | CHRNB2 (0.54) | RAB9AHDAC2P2RX4CHRNB2CHRNA4 | |
| SCHEMBL3830737 | 0.76 | JAK1 (0.39) | RAB9AHDAC2P2RX4CHRNB2CHRNA4 | |
| SCHEMBL3717661 | 0.76 | RAB9A (0.43) | RAB9AHDAC2JAK2JAK1MEN1 | |
| SCHEMBL19122974 | 0.76 | NR1H2 (0.51) | MEN1HPGDKMT2A | |
| SCHEMBL13958616 | 0.76 | NR1H2 (0.51) | MEN1HPGDKMT2A | |
| SCHEMBL13089123 | 0.76 | NR1H2 (0.51) | MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796466-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-1796466-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006002047-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-01-05 | — | — | WO | disclosed |