Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | IDH2 | P48735 | 5/20 | 0.43 |
| ▸ | FABP4 | P15090 | 4/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846891 | 0.88 | IDH2 (0.51) | CNR1PPARGPPARAGRIK1POLB | |
| SCHEMBL3831610 | 0.84 | P2RY14 (0.46) | IDH2KDM4EPTPRFPTPN1TOP2A | |
| SCHEMBL3844021 | 0.82 | IDH2 (0.44) | IDH2PTPRFPTPN1TOP2AGPR35 | |
| SCHEMBL17796921 | 0.80 | FABP4 (0.48) | CNR1FABP4FABP5KDM4EHSD17B10 | |
| SCHEMBL17796963 | 0.80 | FABP4 (0.62) | CNR1GRIK1FABP4FABP5KDM4E | |
| SCHEMBL3831632 | 0.78 | HCRTR1 (0.49) | IDH2 | |
| SCHEMBL16438643 | 0.77 | FABP4 (0.52) | CNR1FABP4FABP5KDM4EHSD17B10 | |
| SCHEMBL17796974 | 0.76 | FABP4 (0.51) | GRIK1FABP4FABP5KDM4EHSD17B10 | |
| SCHEMBL17797031 | 0.76 | FABP4 (0.64) | CNR1GRIK1FABP4FABP5KDM4E | |
| SCHEMBL3825279 | 0.75 | IDH2 (0.56) | IDH2GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765339-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | claimed |
| EP-1765339-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-03-28 | — | — | EP | claimed |
| WO-2006005057-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-01-12 | — | — | WO | claimed |
| EP-1765339-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-1765339-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005057-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-01-12 | — | — | WO | disclosed |