Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 15/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830640 | 0.88 | CNR1 (0.48) | IDH2GRIK1CNR1PPARGPPARA | |
| SCHEMBL3825279 | 0.84 | IDH2 (0.56) | IDH2 | |
| SCHEMBL3827067 | 0.82 | IDH2 (0.52) | IDH2 | |
| SCHEMBL28292961 | 0.80 | MAPT (0.60) | IDH2FABP4POLB | |
| SCHEMBL5099112 | 0.80 | FABP4 (0.62) | IDH2GRIK1FABP4 | |
| SCHEMBL3825545 | 0.79 | IDH2 (0.53) | IDH2 | |
| SCHEMBL3831632 | 0.78 | HCRTR1 (0.49) | IDH2 | |
| SCHEMBL16098694 | 0.76 | ITGB3 (0.48) | IDH2 | |
| SCHEMBL16098691 | 0.76 | ITGB3 (0.48) | IDH2 | |
| SCHEMBL3831610 | 0.75 | P2RY14 (0.46) | IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765339-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-1765339-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005057-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-01-12 | — | — | WO | disclosed |