Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 6/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923658 | 0.79 | SRC (0.45) | SRCSMN1; SMN2TP53KDM4EMAPK1 | |
| SCHEMBL2998324 | 0.79 | SRC (0.45) | SRCSMN1; SMN2TP53KDM4EMAPK1 | |
| SCHEMBL3278550 | 0.78 | MTNR1A (0.36) | SMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL3272172 | 0.75 | KCNH2 (0.35) | PDE2APDE10A | |
| SCHEMBL3243876 | 0.75 | SRC (0.43) | SRCSMN1; SMN2TP53KDM4EMAPK1 | |
| SCHEMBL5263274 | 0.73 | CSF1R (0.34) | PDE2APDE10ANPSR1 | |
| SCHEMBL3828983 | 0.72 | KDM4E (0.42) | CYP17A1CYP11B1CYP11B2SRCSMN1; SMN2 | |
| SCHEMBL29692882 | 0.71 | EGFR (0.41) | PDE2APDE10A | |
| SCHEMBL1075499 | 0.71 | EGFR (0.41) | PDE2APDE10A | |
| SCHEMBL5749051 | 0.70 | KDM4E (0.42) | SMN1; SMN2TP53KDM4EMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796466-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-1796466-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006002047-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-01-05 | — | — | WO | disclosed |