Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185381 | 0.92 | DRD2 (0.48) | RAB9ADRD2DRD3HTR2AHTR2C | |
| SCHEMBL3826601 | 0.89 | RAB9A (0.48) | RAB9APLA2G7DRD2DRD3HTR2A | |
| SCHEMBL3830607 | 0.88 | TACR3 (0.46) | RAB9ADRD2DRD3HTR2AHTR2C | |
| SCHEMBL3825171 | 0.85 | RAB9A (0.53) | RAB9APLA2G7DRD2DRD3HTR2A | |
| Hydrochloric Acid SCHEMBL3822406 | 0.84 | RAB9A (0.52) | RAB9APLA2G7DRD2DRD3HTR2A | |
| SCHEMBL3828851 | 0.83 | RAB9A (0.55) | LMNARAB9ADRD2DRD3HTR2A | |
| SCHEMBL3830147 | 0.82 | SIGMAR1 (0.50) | RAB9APLA2G7DRD2DRD3HTR2A | |
| SCHEMBL3826479 | 0.82 | RAB9A (0.47) | RAB9APLA2G7DRD2DRD3HTR2A | |
| SCHEMBL3826502 | 0.82 | RAB9A (0.45) | RAB9APLA2G7DRD2DRD3HTR2A | |
| Hydrochloric Acid SCHEMBL3823594 | 0.81 | RAB9A (0.46) | RAB9APLA2G7DRD2DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |