Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGAV | P06756 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | NPY2R | P49146 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382456 | 0.92 | ITGB3 (0.47) | ITGB3ITGAVITGA2BNPY2RADRA2A | |
| SCHEMBL382188 | 0.92 | ITGB3 (0.49) | ITGB3ITGAVITGA2BADRA2ADRD2 | |
| SCHEMBL6497814 | 0.91 | ITGB3 (0.41) | ITGB3ITGAVITGA2BADRA2AMCHR1 | |
| SCHEMBL383158 | 0.90 | ITGB3 (0.44) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL6499244 | 0.88 | CNR1 (0.38) | ITGB3ITGAVITGA2BADRA2AKCNH2 | |
| SCHEMBL383437 | 0.88 | ITGB3 (0.47) | ITGB3ITGAVITGA2BNPY2RADRA2A | |
| SCHEMBL383012 | 0.88 | ITGB3 (0.46) | ITGB3ITGAVITGA2BADRA2ADRD2 | |
| SCHEMBL383350 | 0.87 | CASR (0.42) | ITGB3ITGAVITGA2BMCHR1 | |
| SCHEMBL383252 | 0.87 | CASR (0.42) | ITGB3ITGAVITGA2BMCHR1 | |
| SCHEMBL382297 | 0.86 | ITGB3 (0.44) | ITGB3ITGAVITGA2BADRA2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |