Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.47 |
| ▸ | ITGAV | P06756 | 7/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.47 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382456 | 0.96 | ITGB3 (0.47) | ITGB3ITGAVITGA2BVDRSLC6A9 | |
| SCHEMBL383012 | 0.91 | ITGB3 (0.46) | ITGB3ITGAVITGA2BHTR1AADRA2A | |
| SCHEMBL6497814 | 0.90 | ITGB3 (0.41) | ITGB3ITGAVITGA2BVDRHTR1A | |
| SCHEMBL382332 | 0.90 | ITGB3 (0.37) | ITGB3ITGAVITGA2BSLC6A9LMNA | |
| SCHEMBL383095 | 0.88 | ITGB3 (0.46) | ITGB3ITGAVITGA2BNPY2RADRA2A | |
| SCHEMBL382188 | 0.87 | ITGB3 (0.49) | ITGB3ITGAVITGA2BHTR1AADRA2A | |
| SCHEMBL382297 | 0.86 | ITGB3 (0.44) | ITGB3ITGAVITGA2BLMNAHTR1A | |
| SCHEMBL382653 | 0.85 | ITGB3 (0.58) | ITGB3ITGAVITGA2BVDRSLC6A9 | |
| SCHEMBL383158 | 0.85 | ITGB3 (0.44) | ITGB3ITGAVITGA2BLMNAGAA | |
| SCHEMBL382643 | 0.84 | ITGB3 (0.52) | ITGB3ITGAVITGA2BVDRSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |