Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.40 |
| ▸ | ITGAV | P06756 | 9/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383374 | 0.86 | ITGB3 (0.55) | ITGB3ITGAVITGA2BNPY2RMTTP | |
| SCHEMBL381824 | 0.85 | ITGB3 (0.38) | ITGB3ITGAVITGA2BEPHX2DRD2 | |
| SCHEMBL382801 | 0.85 | ITGAV (0.46) | ITGB3ITGAVITGA2B | |
| SCHEMBL382203 | 0.84 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL382290 | 0.82 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL382611 | 0.82 | ITGB3 (0.47) | ITGB3ITGAVITGA2B | |
| SCHEMBL381745 | 0.82 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL382873 | 0.81 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL381767 | 0.81 | ITGB3 (0.51) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL381829 | 0.81 | ITGB3 (0.57) | ITGB3ITGAVITGA2BDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |