Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29812934 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2MIFABCB11ALDH1A1 | |
| SCHEMBL27646743 | 0.85 | GABRA1 (0.41) | GABRA1GABRB2MIFABCB11ALDH1A1 | |
| SCHEMBL158972 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2MIFABCB11ALDH1A1 | |
| SCHEMBL15589311 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2MIFABCB11ALDH1A1 | |
| SCHEMBL2304718 | 0.82 | GABRA1 (0.39) | GABRA1GABRB2MIFABCB11ALDH1A1 | |
| SCHEMBL18247253 | 0.80 | GABRA1 (0.42) | GABRA1GABRB2MIFALDH1A1CYP3A4 | |
| SCHEMBL9535737 | 0.80 | MIF (0.41) | GABRA1GABRB2MIFABCB11ALDH1A1 | |
| SCHEMBL22395496 | 0.80 | GABRA1 (0.38) | GABRA1GABRB2MIFABCB11ALDH1A1 | |
| SCHEMBL10326019 | 0.78 | GABRA1 (0.38) | GABRA1GABRB2MIFP2RY6 | |
| SCHEMBL23629039 | 0.78 | TDP1 (0.41) | GABRA1GABRB2ALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084759-A1 | FLUORESCENT DYE OIL TRACER COMPOSITIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2025-03-13 | — | — | US | claimed |
| US-20230399942-A1 | FLUORESCENT DYE OIL TRACER COMPOSITIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2023-12-14 | — | — | US | claimed |
| CN-115411362-A | Electrolyte for lithium ion battery, lithium ion battery and preparation method thereof | 江苏海四达电源有限公司 | 2022-11-29 | — | — | CN | claimed |
| CN-105951550-A | Construction method for cement concrete subgrade | 四川理工学院 | 2016-09-21 | — | — | CN | claimed |
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (WUXI) COMPANY, INC. (CN) | 2016-09-01 | — | — | US | claimed |
| EP-3034076-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (Wuxi) COMPANY, Inc. (CN) | 2016-06-22 | — | — | EP | claimed |
| CN-105267967-A | Combined application of isothiocyanate-type compound and anti-cancer drug acting or affecting DNA | WUXI JC PHARMACAUTICAL TECHNOLOGY INC | 2016-01-27 | — | — | CN | claimed |
| CN-104415332-A | Combined application between isothiocyanate-type compound and kinase inhibitor medicine in treatment of cancer | WUXI JC PHARMACAUTICAL TECHNOLOGY INC | 2015-03-18 | — | — | CN | claimed |
| CN-104117064-A | Combined application of isothiocyanate compound and hormone medicine | WUXI JC PHARMACAUTICAL TECHNOLOGY INC | 2014-10-29 | — | — | CN | claimed |
| EP-4713378-A1 | ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS | Covestro Deutschland AG (DE) | 2026-03-25 | — | — | EP | disclosed |
| US-12297386-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2025-05-13 | — | — | US | disclosed |
| EP-4237507-B1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2025-04-30 | — | — | EP | disclosed |
| US-20250084759-A1 | FLUORESCENT DYE OIL TRACER COMPOSITIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2025-03-13 | — | — | US | disclosed |
| CN-119431229-A | Condensing agent and application thereof in preparing isothiocyanate | 华为技术有限公司 | 2025-02-14 | — | — | CN | disclosed |
| EP-0048363-A2 | Imidazole derivatives, processes and intermediates for their preparation and drugs containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-03-31 | — | — | EP | disclosed |
| US-4169154-A | Method of treating depression with thiourea derivatives | HOFFMANN-LA ROCHE INC. (US) | 1979-09-25 | — | — | US | disclosed |
| US-4150138-A | Method of reducing blood pressure with thiourea derivatives and guanidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1979-04-17 | — | — | US | disclosed |
| US-4113776-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-4096276-A | Thiourea derivatives for treating hypertension | HOFFMANN-LA ROCHE INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-4066695-A | ANTIHYPERTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | CHUK, KIT, MKI67 | GABRA1 3626/4885GABRB2 3271/4885MIF 986/4885 |
| US-12297386-B2 | Aromatic isothiocyanates | TRPA1, FOXM1, MAFG | GABRA1 3372/4885GABRB2 3469/4885MIF 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.