Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306380 | 0.86 | FNTA (0.40) | L3MBTL1ALDH1A1PKMFNTAFNTB | |
| SCHEMBL1306377 | 0.86 | FNTA (0.40) | L3MBTL1ALDH1A1PKMFNTAFNTB | |
| SCHEMBL1306374 | 0.86 | FNTA (0.40) | L3MBTL1ALDH1A1PKMFNTAFNTB | |
| SCHEMBL3834922 | 0.85 | P2RX3 (0.39) | ALDH1A1KMT2AKDM4EP2RX3TSHR | |
| SCHEMBL3834741 | 0.81 | MEN1 (0.38) | ALDH1A1KMT2AKDM4EP2RX3TSHR | |
| SCHEMBL3832337 | 0.81 | LPAR1 (0.40) | KMT2AP2RX3TSHRLMNA | |
| SCHEMBL3832922 | 0.79 | P2RX3 (0.38) | ALDH1A1CASP1KMT2AKDM4EP2RX3 | |
| SCHEMBL3826815 | 0.79 | TRPM8 (0.38) | ALDH1A1PKMKMT2AKDM4EP2RX3 | |
| SCHEMBL1307064 | 0.78 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1PKMFNTAFNTB | |
| SCHEMBL1307062 | 0.78 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1PKMFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089354-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008054154-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |