Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 5/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3008052 | 0.83 | EGFR (0.48) | GLSEGFRERBB2MAPK8SIGMAR1 | |
| SCHEMBL1448505 | 0.82 | EGFR (0.53) | GLSEGFRERBB2MAPK8MAOB | |
| SCHEMBL5950139 | 0.81 | EGFR (0.49) | GLSEGFRERBB2MAPK8MAOB | |
| SCHEMBL6225809 | 0.81 | MAPK8 (0.43) | MAPK8SIGMAR1 | |
| SCHEMBL6223832 | 0.81 | VNN1 (0.50) | GLSMAPK8MAOBPARP10SIGMAR1 | |
| SCHEMBL3893395 | 0.79 | L3MBTL1 (0.51) | — | |
| SCHEMBL7790183 | 0.79 | EGFR (0.46) | GLSEGFRERBB2FFAR1FFAR4 | |
| SCHEMBL12731510 | 0.78 | EGFR (0.49) | GLSEGFRERBB2MAPK8MAOB | |
| SCHEMBL6226325 | 0.77 | MEN1 (0.51) | THRATHRBMAPK8FFAR1FFAR4 | |
| SCHEMBL16155630 | 0.76 | TAAR1 (0.53) | GLSEGFRERBB2MAPK8PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099760-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008068268-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | WO | disclosed |