Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL140346 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL27934780 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL8009450 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL4287600 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL4355857 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL1727596 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL5745817 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL128012 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL18095558 | 0.97 | ALDH1A1 (0.33) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL4296530 | 0.97 | ALDH1A1 (0.33) | ALDH1A1TSHRL3MBTL1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119362-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | H. LUNDBECK A/S (DK) | 2022-04-21 | — | — | US | disclosed |
| US-11059798-B2 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | H. LUNDBECK A/S (DK) | 2021-07-13 | — | — | US | disclosed |
| US-20200131143-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | H. LUNDBECK A/S (DK) | 2020-04-30 | — | — | US | disclosed |
| US-20190031631-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | H. LUNDBECK A/S (DK) | 2019-01-31 | — | — | US | disclosed |
| US-10118907-B2 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | H. LUNDBECK A/S (DK) | 2018-11-06 | — | — | US | disclosed |
| US-20170158650-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | H. LUNDBECK A/S (DK) | 2017-06-08 | — | — | US | disclosed |
| US-9617231-B2 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | H. LUNDBECK A/S (DK) | 2017-04-11 | — | — | US | disclosed |
| US-20160068497-A1 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | H. LUNDBECK A/S (DK) | 2016-03-10 | — | — | US | disclosed |
| US-9216961-B2 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | H. LUNDBECK A/S (DK) | 2015-12-22 | — | — | US | disclosed |
| US-20150307458-A1 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | H. LUNDBECK A/S (DK) | 2015-10-29 | — | — | US | disclosed |
| US-8575174-B2 | Deuterated 1-piperazino-3-phenyl-indanes for treatment of schizophrenia | H. LUNDBECK A/S (DK) | 2013-11-05 | — | — | US | disclosed |
| US-20130281436-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | H. LUNDBECK A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| US-20120322811-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL-INDANES FOR TREATMENT OF SCHIZOPHRENIA | H. LUNDBECK A/S (DK) | 2012-12-20 | — | — | US | disclosed |
| EP-1650567-B1 | METHOD OF DETECTING PROTEIN DIRT ON CONTACT LENS | MENICON CO LTD (JP) | 2009-10-07 | — | — | EP | disclosed |
| EP-1650567-A1 | METHOD OF DETECTING PROTEIN DIRT ON CONTACT LENS | MENICON CO., LTD. (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-6395737-B1 | ANTICOAGULANTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-05-28 | — | — | US | disclosed |
| CN-1332734-A | Novel malonic acid derivatives, processes for their preparation, their use and pharmaceutical compositions containing them (inhibition of factor xa activity | AVENTIS PHARMA GMBH (DE) | 2002-01-23 | — | — | CN | disclosed |
| EP-1140878-A1 | NOVEL MALONIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ( INHIBITIO OF FACTOR XA ACTIVITY ) | Aventis Pharma Deutschland GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040571-A1 | NOVEL MALONIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM (INHIBITION OF FACTOR XA ACTIVITY) | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-07-13 | — | — | WO | disclosed |
| EP-1016663-A1 | Novel malonic acid derivatives, processes for their preparation, their use and pharmaceutical compositions containing them (inhibition of factor Xa activity) | Aventis Pharma Deutschland GmbH (DE) | 2000-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059798-B2 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | HTR2C, DRD2, HTR2A | ALDH1A1 740/4885TSHR 149/4885L3MBTL1 4292/4885 |
| US-20120322811-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL-INDANES FOR TREATMENT OF SCHIZOPHRENIA | HTR2C, DRD2, HTR2A | ALDH1A1 729/4885TSHR 172/4885L3MBTL1 4250/4885 |
| US-20200131143-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | HTR2C, DRD2, HTR2A | ALDH1A1 740/4885TSHR 149/4885L3MBTL1 4292/4885 |
| US-20130281436-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | HTR2C, DRD2, HTR2A | ALDH1A1 740/4885TSHR 149/4885L3MBTL1 4292/4885 |
| US-20220119362-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | HTR2C, DRD2, HTR2A | ALDH1A1 740/4885TSHR 149/4885L3MBTL1 4292/4885 |
| US-20160068497-A1 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | HTR2C, DRD2, HTR2A | ALDH1A1 740/4885TSHR 149/4885L3MBTL1 4292/4885 |
| US-20170158650-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | HTR2C, DRD2, HTR2A | ALDH1A1 740/4885TSHR 149/4885L3MBTL1 4292/4885 |
| US-20190031631-A1 | DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA | HTR2C, DRD2, HTR2A | ALDH1A1 740/4885TSHR 149/4885L3MBTL1 4292/4885 |
| US-10118907-B2 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | HTR2C, DRD2, HTR2A | ALDH1A1 740/4885TSHR 149/4885L3MBTL1 4292/4885 |
| US-20150307458-A1 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | HTR2C, DRD2, HTR2A | ALDH1A1 740/4885TSHR 149/4885L3MBTL1 4292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.